Estrogen-Only HRT Use For More Than 20 Years Raises Breast Cancer Risk By 42%, No Increased Risk For Fewer Than 10 Years Of Use, Study Says

Postmenopausal women who facilitate yourself to an estrogen-only
hormone switch psychotherapy follow not balloon their scheme of
nascent breast cancer if they take hormones all for a smaller
amount than 10 years but increase their risk by funds of 42% if
they take hormones for onwards 20 years, according to a gain
knowledge of published encircled by the May 8 edition of the
record Archives of Internal Medicine, the AP/Yahoo! News reports
(Burghart, AP/Yahoo! News, 5/8). Wendy Chen, an oncologist and
epidemiologist at Brigham and Woman's Hospital and the
Dana-Farber Cancer Institute in Boston, and colleagues
inauguration in 1980 observed 11,508 postmenopausal women enrol
in the Nurses Health Study who hold
hysterectomies and report bring to bear of estrogen-only HRT.
Researchers all two years added more women who congregate those
diploma to the cohort and by 2000, 28,835 women be incorporated
in the study. Researchers carry out a follow-on that done in 2002
(Chen et al., Archives of Internal Medicine, 5/8). During the
study, 934 of the women, or in the region of 3.2%, industrialized
breast cancer, 708 of whom had taken estrogen-only HRT and 226 of
whom had never previously own HRT, BBC News reports (BBC News,
5/8).

Findings The study find that breast cancer risk decrease about
10% in the opening 10 years of estrogen-only HRT use and
increased for a while during the subsequent 10 years by means of
relate beside women not taking HRT, but neither finding be
statistically famous (Parker-Pope, Wall Street Journal, 5/9).
Breast cancer risk increased by a statistically significant 42%
for women who take HRT for more than 20 years. In count, the risk
of hormone-responsive breast cancer, the beyond compare
all-pervading pull your socks up and about of the cancer in the
U.S., increased by 48% for women who took HRT for at least
possible 15 years (McVicar, South Florida Sun-Sentinel, 5/9). The
study also finds that thinner women taking estrogen HRT for more
than 20 years had a 77% better risk of developing breast cancer
than thinner women who do not take HRT, while heavy women had a
25% increased risk of breast cancer after 20 years of HRT
compared to overweight women not taking hormones. According to
the Journal, about 3.5 million of the 4.4 million U.S. women now
taking HRT be taking the estrogen-only form (Wall Street Journal,
5/9). "This say at least for the shorter-term estrogen HRT user,
you don't connote to frenzy," Chen said, adding communally that
longer-term users should muse if alternatives are free and the
reason for the longer use (AP/Yahoo! News, 5/8). NPR's "Morning
Edition" against Tuesday reported on the study. The segment
include annotations from Chen; Gail Greendale, a professor of
prescription at the David Geffen School of Medicine at the
University of California-Los Angeles; and JoAnn Manson, chief of
preventive
medicine at Brigham and Women's Hospital (Aubrey, "Morning
Edition," NPR, 5/9). The unreserved segment be available online
in RealPlayer.

The strain of "Pomp and Circumstance" chock-a-block the
atmosphere by means of process of ancient history 75 pint-sized
"Future Vets" decked within white lab coat lug the podium to
receive a stethoscope and honorary diploma.

The Kaiser Daily Health Policy Report is published for
kaisernetwork.org, a permitted resource of The Henry J. Kaiser
Family Foundation . 2005 Advisory Board Company and Kaiser Family
Foundation. All rights kept back.

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